Mammalia Linnaeus, 1758
Anagalidae Simpson, 1931
Bradypodidae Gray, 1821
Cyclopedidae Pocock, 1924
Didymoconidae
Entelopidae Ameghino, 1889
Gypsonictopidae Van Valen, 1967
Kulbeckiidae
Leptictidae Gill, 1872
Megalonychidae Ameghino, 1889
Megatheriidae Gray, 1821
Mirandabradys Carlini, Scillato-Yané & Sánchez, 2006
Mylodontidae Gill, 1872
Myrmecophagidae Gray, 1825
Orophodontidae Ameghino, 1894
Pseudictopidae Sulimski, 1969
Rathymotheriidae
Scelidotheriidae
Zalambdalestidae Gregory & Simpson, 1926
